D型流感病毒研究进展

doi:10.11843/j.issn.0366-6964.2018.07.001

摘要/Abstract

摘要：

自2011年从猪体内分离到全球首株D型流感病毒以来，美国、墨西哥、法国、爱尔兰、意大利、中国、日本以及西北非等多个国家或地区报道D型流感病毒在猪、牛、羊群中广泛流行，甚至人抗体呈阳性。遗传进化分析表明D型流感病毒主要分为D/OK和D/660两个谱系，目前我国主要流行的是D/OK谱系，D/660谱系主要在北美地区流行。虽然D型流感病毒主要引起感染动物轻微的呼吸道疾病，但是其可能会进入血液引起病毒血症，给公共卫生安全带来严重威胁。随着D型流感病毒流行范围不断扩大，为提高人们对该病的认识，作者从D型流感病毒特性、流行病学、致病性以及诊断和防治等相关方面的最新研究进展进行概述。

Abstract:

Since the first influenza D virus(IDV) was isolated from swine in 2011, it has been reported that IDVs are widely isolated from swine, cattle and sheep in Mexico, France, Ireland, Italy, China, Japan and northwest Africa. Based on the phylogenetic analysis of whole-genome sequences of these novel influenza viruses, two genetic lineages can be distinguished, D/OK and D/660 lineages. The isolates from China belong to D/OK lineage, and the stains of D/660 lineage are mainly spread in North America. Although IDV can cause mild respiratory disease in susceptible animals, the virus may enter the blood leading to viremia, which poses a serious threat to public health. To raise the awareness about IDV, this review describes the latest researches progress in the study of IDV including its characterization, epidemiology, pathogenicity, diagnosis and prevention.

中图分类号:

S852.659.5

高晓龙, 韦海涛, 宋彦军, 王跃, 殷雨晴, 王林, 梅力, 冯小宇. D型流感病毒研究进展[J]. 畜牧兽医学报, 2018, 49(7): 1327-1333.

GAO Xiao-long, WEI Hai-tao, SONG Yan-jun, WANG Yue, YIN Yu-qing, WANG Lin, MEI Li, FENG Xiao-yu. Progress Research of Influenza D Virus[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2018, 49(7): 1327-1333.

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